Choice of anesthesia and data analysis method strongly increases sensitivity of 18F-FDG PET imaging during experimental epileptogenesis.

Ina JahreisPablo BascuñanaTobias L RossJens P BankstahlMarion Bankstahl

Published in: PloS one (2021)

This study reveals evaluation of anesthesia protocols for preclinical 18F-FDG PET imaging as a critical step in the study design. Together with an appropriate data analysis workflow, the chosen anesthesia protocol may uncover otherwise concealed disease-associated regional glucometabolic changes.

Keyphrases

pet imaging
data analysis
positron emission tomography
randomized controlled trial
computed tomography
stem cells
cell therapy
electronic health record
decision making