Tumor-infiltrating CD39+CD8+ T cells determine poor prognosis and immune evasion in clear cell renal cell carcinoma patients.

Yu QiYu XiaZhiyuan LinYang QuYangyang QiYifan ChenQuan ZhouHan ZengJiajun WangYuan ChangQi BaiYiwei WangYu ZhuLe XuLingli ChenYunyi KongWeijuan ZhangBo DaiLi LiuJianming GuoJiejie Xu

Published in: Cancer immunology, immunotherapy : CII (2020)

High CD39+CD8+ T cells indicated poor prognosis in ccRCC, due to impaired anti-tumor function of CD39+CD8+ T cells and indicated therapeutic benefit of TKIs therapy.

Keyphrases

poor prognosis
long non coding rna
end stage renal disease
ejection fraction
newly diagnosed
chronic kidney disease
nk cells
prognostic factors
stem cells
patient reported outcomes
mesenchymal stem cells