The role of CDH2 and MCP-1 mRNAs of blood extracellular vesicles in predicting early-stage diabetic nephropathy.

Hojat DehghanbanadakiKatayoon ForouzanfarArdeshir KakaeiSamaneh ZeidiNegar SalehiBabak ArjmandFarideh RaziEhsan Hashemi

Published in: PloS one (2022)

CDH2 and MCP-1 mRNAs expression in blood EVs was decreased with the development of DN, suggesting the renoprotective effect of these mRNAs in diabetic individuals. Moreover, their quantifications could serve as diagnostic biomarkers for early-stage DN.

Keyphrases

early stage
diabetic nephropathy
poor prognosis
sentinel lymph node
genome wide analysis
type diabetes
wound healing
squamous cell carcinoma
long non coding rna
lymph node