Type 2 diabetes linked FTO gene variant rs8050136 is significantly associated with gravidity in gestational diabetes in a sample of Bangladeshi women: Meta-analysis and case-control study.
U S Mahzabin AminTahia Anan RahmanMashfiqul HasanTania TofailMuhammad Abul HasanatZeba Islam SerajMd SalimullahPublished in: PloS one (2023)
Our meta-analysis revealed a significant association between SNP rs8050136 of FTO with T2DM, and this variant was substantially associated with an increased risk of GDM in a sample of Bangladeshi multigravida women.
Keyphrases
- systematic review
- type diabetes
- polycystic ovary syndrome
- pregnancy outcomes
- meta analyses
- genome wide
- cardiovascular disease
- glycemic control
- case control
- insulin resistance
- copy number
- randomized controlled trial
- pregnant women
- gene expression
- metabolic syndrome
- adipose tissue
- high density
- transcription factor
- weight loss