Hepatic CYP2B10 is highly induced by binge ethanol and contributes to acute-on-chronic alcohol-induced liver injury.

Bryan MackowiakMingjiang XuYuhong LinYukun GuanWonhyo SeoRuixue RenDechun FengJace W JonesHongbing WangBin Gao

Published in: Alcoholism, clinical and experimental research (2022)

Hepatic Cyp2b10 expression is highly induced after ethanol binge, and such upregulation reduces acute-on-chronic ethanol-induced liver injury via the indirect modification of ethanol metabolism.

Keyphrases

drug induced
liver failure
poor prognosis
respiratory failure
aortic dissection
high glucose
cell proliferation
diabetic rats
signaling pathway
long non coding rna
intensive care unit
alcohol consumption
stress induced