Neurobiological correlation between phosphorylated tau and mood symptoms in memory clinic patients.

Takashi Ozaki Naoki Hashimoto Niki Udo Hisashi NaritaShin NakagawaIchiro Kusumi

Published in: Psychogeriatrics : the official journal of the Japanese Psychogeriatric Society (2023)

We provide new evidence for a negative correlation between p-tau and depression and apathy of NPS, which may be influenced by APOE ε4. Future longitudinal studies are required to confirm the utility of p-tau for predicting the course of mood symptoms in patients with cognitive decline.

Keyphrases

cognitive decline
sleep quality
mild cognitive impairment
end stage renal disease
cerebrospinal fluid
bipolar disorder
chronic kidney disease
newly diagnosed
ejection fraction
depressive symptoms
working memory
cross sectional
patient reported outcomes
current status
patient reported
case control