Expression of HLA-DR by mesenchymal stromal cells in the platelet lysate era: an obsolete release criterion for MSCs?
Zyrafete KuçiNatascha PiedeKathrin VogelsangLisa-Marie PfeffermannSibylle WehnerEmilia Salzmann-ManriqueMiriam StaisHermann KreyenbergHalvard BonigPeter BaderSelim KuçiPublished in: Journal of translational medicine (2024)
Irrespective of HLA-DR expression at the population level, all MSC preparations significantly inhibited the proliferation of stimulated peripheral blood mononuclear cells, indicating that HLA-DR represents an obsolete release marker for the clinical use of MSCs.