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Chairside molecular imaging of aberrant glycosylation in subjects with suspicious oral lesions using fluorescently labeled wheat germ agglutinin.

John BaetenAlexander JohnsonSumsum SunnyAmritha SureshPraveen BirurK UmaDeepak Kademani
Published in: Head & neck (2017)
This study supports in vivo fluorescent molecular imaging of WGA-FITC to visualize aberrant sialic acid expression associated with carcinogenesis. This technique resulted in the immediate chairside detection of oral cancerous and dysplastic lesions.
Keyphrases
  • poor prognosis
  • label free
  • quantum dots
  • living cells
  • pet imaging
  • binding protein
  • cell surface