Phenotypic expression, genotypic profiling and clinical outcomes of infantile hypertrophic cardiomyopathy: a retrospective study.
Hisham AhamedShruti VargheseGeorg GutajahrBalu VaidyanathanMahesh KappanayilNavaneetha SasikumarShine KumarAparna HariMalavika KrishnakumarRaman Krishna KumarPublished in: Archives of disease in childhood (2024)
This cohort demonstrates the morphological, functional and genetical heterogeneity of infantile HCM, enunciating the need for integration of cardiology, metabolic and genetic services to achieve optimum outcomes in these patients.
Keyphrases
- hypertrophic cardiomyopathy
- end stage renal disease
- left ventricular
- ejection fraction
- healthcare
- newly diagnosed
- single cell
- poor prognosis
- chronic kidney disease
- primary care
- peritoneal dialysis
- mental health
- heart failure
- cardiac surgery
- gene expression
- genome wide
- dna methylation
- binding protein
- copy number
- acute kidney injury
- patient reported outcomes
- weight loss
- insulin resistance