Proteomic and Metabolomic Characterization of Metabolically Healthy Obesity: A Descriptive Study from a Swedish Cohort.
J KordunerPeter M NilsssonOlle MelanderMathias J GerlGunnar EngströmErasmus BachusMartin MagnussonFilip OttossonPublished in: Journal of obesity (2021)
Compared to MUO individuals, corresponding MHO individuals present with a more favorable lipid metabolic profile, accompanied by a downregulation of potentially harmful proteomic biomarkers. This unique and extensive biomarker profiling presents novel data on potentially differentiating traits between these two obese phenotypes.
Keyphrases
- weight loss
- metabolic syndrome
- type diabetes
- insulin resistance
- adipose tissue
- label free
- signaling pathway
- electronic health record
- big data
- bariatric surgery
- weight gain
- genome wide
- high fat diet induced
- fatty acid
- machine learning
- contrast enhanced
- gene expression
- computed tomography
- body mass index
- artificial intelligence