Reduced KLK2 expression is a strong and independent predictor of poor prognosis in ERG-negative prostate cancer.

Sarah BonkMartina KluthKristina JansenClaudia Hube-MaggGeorgia Makrypidi-FrauneDoris HöflmayerSören WeidemannKatharina MöllerRia UhligFranziska BüscheckAndreas M LuebkeEike BurandtTill S ClauditzStefan SteurerThorsten SchlommHartwig HulandHans HeinzerGuido SauterRonald SimonDavid Dum

Published in: The Prostate (2020)

Loss of KLK2 expression is a potentially useful prognostic marker in prostate cancer. Analysis of KLK2 alone or in combination with PSA may be useful for estimating cancer aggressiveness at the time of biopsy.

Keyphrases

poor prognosis
prostate cancer
long non coding rna
radical prostatectomy
papillary thyroid
squamous cell carcinoma
ultrasound guided
fine needle aspiration
binding protein