Expression of MAPK and PI3K/AKT/mTOR Proteins according to the Chronic Liver Disease Etiology in Hepatocellular Carcinoma.

Paulo Henrique Costa Diniz Serena Dafne do Carmo Silva Paula Vieira Teixeira Vidigal Marcelo Antônio Pascoal Xavier Cristiano X Lima Luciana Costa Faria Teresa Cristina de Abreu Ferrari

Published in: Journal of oncology (2020)

Hepatitis B and C virus can lead to HCC by different mechanisms compared with nonviral hepatopathy. KRAS and PI3K may have a role in carcinogenesis. The prognostic and therapeutic implications need to be investigated.

Keyphrases

poor prognosis
signaling pathway
oxidative stress
atomic force microscopy
pi k akt
wild type
long non coding rna
cell proliferation
drug induced