The dilemma of open or double-blind food challenges in diagnosing food allergy in children: Design of the ALDORADO trial.
Wouter W de WegerAline B SprikkelmanCatherina E M HerpertzGerbrich N van der MeulenJudith M VonkArvid W A KampsGerard H KoppelmannPublished in: Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology (2021)
There is an urgent need to investigate the diagnostic accuracy of different oral food challenge protocols. We present the rationale and design of the ALDORADO trial (ALlergy Diagnosed by Open oR DOuble-blind food challenge) that has been set up to investigate whether the outcome of the open food challenge is comparable to DBPCFC.