Loss of TSC1 in secondary angiosarcoma of the breast.
Lucy RoseNicci Owusu-BrackettStephen MooreBridget A OppongPublished in: Clinical case reports (2023)
Post-radiation angiosarcoma of the breast is rare and associated with a poor prognosis. This case presents the first loss of function mutation in TSC1 in breast radiation-induced angiosarcoma. Evaluation of these markers can aid in identifying potential therapeutic targets.