Efficacy of various treatment modalities for nCOV-2019: A systematic review and meta-analysis.
Shubham MisraManabesh NathVijay HaddaDeepti VibhaPublished in: European journal of clinical investigation (2020)
Our meta-analysis suggests that except in vitro studies, no treatment has shown overall favourable outcomes in nCOV-2019 patients. Lopinavir-ritonavir, remdesivir and tocilizumab may have some benefits, while hydroxychloroquine administration may cause harm in nCOV-2019 patients. Results from upcoming large clinical trials may further clarify role of these drugs.
Keyphrases
- end stage renal disease
- systematic review
- clinical trial
- ejection fraction
- chronic kidney disease
- newly diagnosed
- peritoneal dialysis
- prognostic factors
- rheumatoid arthritis
- type diabetes
- systemic lupus erythematosus
- randomized controlled trial
- patient reported outcomes
- skeletal muscle
- metabolic syndrome
- insulin resistance
- replacement therapy
- open label
- phase ii