Human decidual mesenchymal stem cells obtained from early pregnancy attenuate bleomycin-induced lung fibrosis by inhibiting inflammation and apoptosis.

Guangyao NingXiaohui GuoKechao ZhuZiqiang XuPeian CaiYan DangChen LuFeng XuRuifang ShenNingning KangRenquan ZhangKegong Chen

Published in: International immunopharmacology (2024)

DMSCs exhibited better efficacy in improving pulmonary inflammation and lung fibrosis than BMSCs. Thus, DMSCs are a potential therapeutic target for pulmonary fibrosis.

Keyphrases

pulmonary fibrosis
oxidative stress
diabetic rats
mesenchymal stem cells
endothelial cells
high glucose
pulmonary hypertension
signaling pathway
endoplasmic reticulum stress
umbilical cord
bone marrow
pluripotent stem cells
liver fibrosis
drug induced
stem cells
cell therapy