Multistability and hysteresis in states of oral microbiota: Is it impacting the dental clinical cohort studies?
Utkarsh MangalKowoon NohSeeyoon LeeJae-Kook ChaJe Seon SongJung-Yul ChaKee-Joon LeeKwang-Mahn KimSeong-Soo KangSung-Hwan ChoiPublished in: Journal of periodontal research (2023)
Our observations indicate towards the presence of multistable states within the oral microbiome in an intervention-free healthy cohort. For a conclusive and meaningful long-term reference, dental clinical research should account for multistability in the personalized therapy approach to improve the identification and classification of reliable markers.