Klotho Gene in Human Salt-Sensitive Hypertension.
Lorena CitterioSimona Delli CarpiniSara LupoliElena BrioniMarco SimoniniSimone FontanaLaura ZagatoElisabetta MessaggioCristina BarlassinaDaniele CusiPaolo ManuntaChiara LanzaniPublished in: Clinical journal of the American Society of Nephrology : CJASN (2020)
KL rs9536314 is associated with salt-sensitive hypertension in patients with hypertension who are treatment naive. Moreover, circulating α-Klotho levels were mainly related to diastolic BP changes at the end of a salt load and to eGFR as an expression of kidney aging.