Klotho Gene in Human Salt-Sensitive Hypertension.

Lorena CitterioSimona Delli CarpiniSara LupoliElena BrioniMarco SimoniniSimone FontanaLaura ZagatoElisabetta MessaggioCristina BarlassinaDaniele CusiPaolo ManuntaChiara Lanzani

Published in: Clinical journal of the American Society of Nephrology : CJASN (2020)

KL rs9536314 is associated with salt-sensitive hypertension in patients with hypertension who are treatment naive. Moreover, circulating α-Klotho levels were mainly related to diastolic BP changes at the end of a salt load and to eGFR as an expression of kidney aging.

Keyphrases

blood pressure
endothelial cells
small cell lung cancer
poor prognosis
epidermal growth factor receptor
gene expression
tyrosine kinase
heart failure
arterial hypertension
atrial fibrillation
binding protein
combination therapy