Dolutegravir Monotherapy as Maintenance Strategy: A Meta-Analysis of Individual Participant Data From Randomized Controlled Trials.
Anna L FournierLaurent HocquelouxDominique L BraunKarin J MetznerRoger D KouyosFrançois RaffiAnaïs R BriantEsteban MartinezElisa De LazzariEugenia NegredoBart RijndersCasper RokxHuldrych F GünthardJean-Jacques ParientiPublished in: Open forum infectious diseases (2022)
Our study supports the importance of a large viral reservoir size for explaining DTG-m simplification strategy failure. Further studies are needed to link size and genetic diversity of the HIV-1 reservoir.
Keyphrases
- genetic diversity
- antiretroviral therapy
- randomized controlled trial
- hiv positive
- hiv infected
- human immunodeficiency virus
- hiv aids
- sars cov
- hepatitis c virus
- hiv testing
- hiv infected patients
- water quality
- combination therapy
- open label
- clinical trial
- men who have sex with men
- machine learning
- south africa
- case control
- artificial intelligence
- data analysis