Predicting treatment response and clinicopathological findings in lupus nephritis with urine epidermal growth factor, monocyte chemoattractant protein-1 or their ratios.
Pintip NgamjanyapornSuchin WorawichawongPrapaporn PisitkunKhantong KhiewngamSurasak KantachuvesiriArkom NongnuchMontira AssanathamNuankanya SathirapongsasutiChagriya KitiyakaraPublished in: PloS one (2022)
MCP-1 increased with disease activity, whereas EGF decreased with low GFR and chronic damage. Urine EGF may be a promising biomarker to predict therapeutic response in LN. EGF/MCP-1 did not improve the prediction of response.