Predicting future amyloid biomarkers in dementia patients with machine learning to improve clinical trial patient selection.
Fabian H ReithElizabeth C MorminoGreg ZaharchukPublished in: Alzheimer's & dementia (New York, N. Y.) (2021)
Predicting quantitative biomarkers on future images using machine learning methods consisting of deep image features combined with clinical data may allow better targeting of treatments or enrollment in clinical trials.
Keyphrases
- clinical trial
- deep learning
- machine learning
- current status
- big data
- phase ii
- mild cognitive impairment
- open label
- artificial intelligence
- convolutional neural network
- case report
- study protocol
- electronic health record
- high resolution
- double blind
- health insurance
- optical coherence tomography
- healthcare
- randomized controlled trial