MicroRNAs as Biomarkers of Pain Intensity in Patients With Chronic Fatigue Syndrome.

Hadeel A Al-RawafAhmad H AlghadirSami A Gabr

Published in: Pain practice : the official journal of World Institute of Pain (2019)

The intensity and consequences of pain were influenced by differential expression of miR-558, miR-146a, miR-150, miR-124, and miR-143, which was directly associated with higher expression of the immune inflammatory-related genes TNFα, IL-6, and COX-2 in adolescents with CFS. Further studies of larger patient cohorts will help clarify the role of miRNAs in the pathogenesis of CFS.

Keyphrases

cell proliferation
long non coding rna
long noncoding rna
poor prognosis
chronic pain
pain management
young adults
rheumatoid arthritis
neuropathic pain
high intensity
case report
oxidative stress
binding protein
sleep quality