Impact of a diet and activity health promotion intervention on regional patterns of DNA methylation.
Elizabeth A HiblerLei HuangJorge AndradeBonnie SpringPublished in: Clinical epigenetics (2019)
The results demonstrate that the MBC2 diet and physical activity intervention impacts patterns of DNA methylation in gene regions related to cell cycle regulation and carcinogenesis. Future studies will examine DNA methylation as a biomarker to identify populations that may particularly benefit from incorporating health behavior change into plans for precision prevention.
Keyphrases
- dna methylation
- cell cycle
- health promotion
- physical activity
- genome wide
- randomized controlled trial
- gene expression
- copy number
- cell proliferation
- weight loss
- healthcare
- public health
- mental health
- body mass index
- current status
- risk assessment
- case control
- genome wide identification
- genetic diversity
- transcription factor