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Childhood maltreatment and risk of endocrine diseases: an exploration of mediating pathways using sequential mediation analysis.

Shu WenJianwei ZhuXin HanYuchen LiHaowen LiuHuazhen YangCan HouShishi XuJunren WangYao HuYuanyuan QuDi LiuThor AspelundFang FangUnnur A ValdimarsdóttirHuan Song
Published in: BMC medicine (2024)
Our study demonstrates that adverse psychological sequel of childhood maltreatment constitutes the main pathway to multiple endocrine diseases, particularly type 2 diabetes and HPA-axis-related endocrine diseases. Therefore, increased access to evidence-based mental health services may also be pivotal in reducing the risk of endocrine diseases among childhood maltreatment-exposed individuals.
Keyphrases
  • type diabetes
  • early life
  • cardiovascular disease
  • physical activity
  • social support
  • adipose tissue
  • young adults
  • weight loss
  • electronic health record
  • drug induced
  • patient reported