Detection of multiple sclerosis lesions in the cervical cord: which of the MAGNIMS 'mandatory' non-gadolinium enhanced sagittal sequences is optimal at 3T?
Chian A ChangAbigail L ChongRonil V ChandraErnest ButlerDeepa RajendranKenneth ChuahStephen L StuckeyPublished in: The neuroradiology journal (2021)
This study provides the necessary evidentiary support at 3T for the magnetic resonance imaging in multiple sclerosis spinal magnetic resonance imaging protocol consensus guidelines. At 3T sagittal proton density-weighted fast spin echo and short tau inversion recovery sequences allowed improved detection of cervical spinal cord multiple sclerosis lesions, compared to T2-weighted fast spin echo and three-dimensional double inversion recovery magnetic resonance imaging. Utilising T2-weighted fast spin echo alone at 3T is insufficient for lesion detection.
Keyphrases
- contrast enhanced
- magnetic resonance imaging
- multiple sclerosis
- diffusion weighted
- magnetic resonance
- spinal cord
- diffusion weighted imaging
- computed tomography
- loop mediated isothermal amplification
- room temperature
- label free
- single molecule
- white matter
- real time pcr
- density functional theory
- clinical practice
- spinal cord injury
- randomized controlled trial
- neuropathic pain
- cerebrospinal fluid
- quantum dots
- sensitive detection