Outcomes in the ISCHEMIA Trial Based on Coronary Artery Disease and Ischemia Severity.
Harmony R ReynoldsLeslee J ShawJames K MinCourtney B PageDaniel S BermanBernard R ChaitmanMichael H PicardRaymond Y KwongSean M O'BrienZhen HuangDaniel B MarkRanjith Kumar NathSudhanshu K DwivediPaola E P SmanioPeter H StoneClaes HeldMatyas KeltaiSubhash BanerjeeJonathan D NewmanJohn A SpertusGregg W StoneDavid J MaronJudith S HochmanPublished in: Circulation (2021)
Ischemia severity was not associated with increased risk after adjustment for CAD severity. More severe CAD was associated with increased risk. Invasive management did not lower all-cause mortality at 4 years in any ischemia or CAD subgroup. Registration: URL: https://www.clinicaltrials.gov. Unique identifier: NCT01471522.