Ultrasound evaluation of joint damage and disease activity in adult patients with severe haemophilia A using the HEAD-US system.
Victor Jimenez YusteHortensia de la Corte-RodríguezMaria Teresa Alvarez-RomanMónica Martín-SalcesFelipe QuerolSaturnino Haya GuaitaMaria-Eva Mingot-CastellanoNuria Fernández-MosteirínMariana CanaroAmparo SantamaríaRamiro NúñezLuis Javier García-FradeCarlo MartinoliHae Kyung KimPublished in: Haemophilia : the official journal of the World Federation of Hemophilia (2021)
Joint function may be effectively preserved in patients with SHA on PP, but OD treatment or later initiation of prophylaxis does not seem to prevent progression of arthropathy. Disease worsening was observed in patients OD, TP or IP, most often affecting ankles and elbows. Closer ultrasound imaging monitoring may improve management of these patients.
Keyphrases
- end stage renal disease
- disease activity
- ejection fraction
- newly diagnosed
- chronic kidney disease
- rheumatoid arthritis
- magnetic resonance imaging
- oxidative stress
- prognostic factors
- computed tomography
- rheumatoid arthritis patients
- early onset
- patient reported outcomes
- combination therapy
- optical coherence tomography
- optic nerve
- replacement therapy