Effects of estradiol on bone in men undergoing androgen deprivation therapy: a randomized placebo-controlled trial.

Nicholas RussellAli Ghasem-ZadehRudolf Hoermann Ada Sau-Zhuen CheungJeffrey D ZajacCat Shore-LorentiPeter R EbelingDavid J Handelsman Mathis Grossmann

Published in: European journal of endocrinology (2022)

Relative to placebo, E2 treatment increases some measures of bone density and bone strength in men and reduces bone remodelling, effects that occur in the absence of endogenous T.

Keyphrases

bone mineral density
soft tissue
bone loss
randomized controlled trial
stem cells
double blind
clinical trial
mesenchymal stem cells
study protocol
estrogen receptor
cell therapy
replacement therapy
smoking cessation