Efficacy and Safety of Dexmedetomidine Compared to Other Needle-Free Pharmacological Sedation Methods in Pediatric Patients Undergoing Imaging Procedures.
Mohammed Alsabri Hussein AlsabriAbdelrahman AbdelshafiAhmed Bostamy ElsnhoryNoha Samir SelimAlaa Bostamy ElsnhoryDouaa AlbelalFatima AkramAlaa Ahmed ElshanbaryPublished in: Pediatric emergency care (2024)
Dexmedetomidine demonstrates effectiveness in pediatric MRI/CT sedation, offering advantages over midazolam and similar efficacy to chloral hydrate. Careful cardiovascular monitoring is essential during administration, particularly in patients with congenital heart disease. Sublingual and intranasal administration of dexmedetomidine is a viable option with high bioavailability. This meta-analysis contributes valuable insights into refining sedation protocols for pediatric imaging procedures, emphasizing efficacy and safety considerations.
Keyphrases
- systematic review
- patients undergoing
- high resolution
- end stage renal disease
- cardiac surgery
- contrast enhanced
- magnetic resonance imaging
- randomized controlled trial
- chronic kidney disease
- computed tomography
- ejection fraction
- peritoneal dialysis
- acute kidney injury
- meta analyses
- image quality
- magnetic resonance
- acute respiratory distress syndrome
- diffusion weighted imaging