A Simple Model for Inducing Optimal Increase of SDF-1 with Aminoglycoside Ototoxicity.

Hyun Mi JuSun Hee LeeJin Sil ChoiYoung Joon Seo

Published in: BioMed research international (2017)

We observed optimal induction of the stem cell homing factor in the newly generated aminoglycoside-induced ototoxicity mouse model using a "one-shot" protocol. This study regarding high SDF-1 levels in our mouse model of ototoxicity would play a major role in the development of therapeutic agents using MSC homing.

Keyphrases

mouse model
stem cells
pseudomonas aeruginosa
acinetobacter baumannii
randomized controlled trial
high glucose
diabetic rats
mesenchymal stem cells
multidrug resistant