Critical update, systematic review, and meta-analysis of oral erythroplakia as an oral potentially malignant disorder.

Alejandro Ismael Lorenzo-Pouso Irene Lafuente-Ibáñez de Mendoza Mário Pérez-Sayáns Alba Pérez Jardón Cintia Micaela Chamorro-Petronacci Andrés Blanco Carrión José Manuel Aguirre-Urízar

Published in: Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology (2022)

Overall malignant development rate of OE in the meta-analysis was 19.9%. We could not associate any specific clinicopathological feature with the malignant development. The presence of epithelial dysplasia in the initial biopsy remains the worst prognostic factor. Further observational studies on OE are needed, with well-established diagnostic criteria and good clinical follow-up, in order to identify the true risk of malignant development of oral erythroplakia and the related risk factors.

Keyphrases

prognostic factors
systematic review
risk factors
machine learning
randomized controlled trial
ultrasound guided