Variant of SNPs at lncRNA NEAT1 contributes to gastric cancer susceptibility in Chinese Han population.

Xuanke JiYali YanNan MaGui HeKaijuan WangYuehua ZhangJingjing YinChunhua SongPeng WangHua YeLiping DaiJianying ZhangKaijuan Wang

Published in: International journal of clinical oncology (2021)

We found that the genetic variations in NEAT1 were significantly associated with risk of gastric cancer. The G > A variant of rs3825071 may confer gastric cancer susceptibility by changed biological effects to increase the expression of NEAT1.

Keyphrases

genome wide
poor prognosis
long non coding rna
gene expression
binding protein