Rational design of a red-light absorbing ruthenium polypyridine complex as a photosensitizer for photodynamic therapy.

Alessia FennesNicolás MontesdeocaZisis PapadopoulosJohannes Karges

Published in: Chemical communications (Cambridge, England) (2024)

Herein, the computer-guided design, chemical synthesis, and biological evaluation of a RuC polypyridine complex, that could eradicate cancerous cells upon excitation with red light at 630 nm, is reported.

Keyphrases

photodynamic therapy
fluorescence imaging
induced apoptosis
cell cycle arrest
deep learning
cell proliferation
machine learning
energy transfer
quantum dots