Johannes Karges

ORCID

Publication Activity (10 Years)

Years Active: 2019-2024
Publications (10 Years): 72

Top Venues

Chemical science

Journal of medicinal chemistry

Chemistry (Weinheim an der Bergstrasse, Germany)

Dalton transactions (Cambridge, England : 2003)

Paris Sciences et Lettres (PHD)

This page only lists publications with an associated author ORCID identifier.

Education History

Paris Sciences et Lettres

France

PHD

Sun Yat-Sen University

China

PHD

Philipps-Universität Marburg

Germany

MSC

Philipps-Universität Marburg

Germany

BSC

Publications

Ganghao Liang, Wanqing Cao, Dongsheng Tang, Hanchen Zhang, Yingjie Yu, Jian-Xun Ding, Johannes Karges, Haihua Xiao
Nanomedomics. ACS nano 18 (17) (2024)
Haobing Wang, Yidan Lai, Dan Li, Johannes Karges, Pingyu Zhang, Huaiyi Huang
Self-Assembly of Erlotinib-Platinum(II) Complexes for Epidermal Growth Factor Receptor-Targeted Photodynamic Therapy. Journal of medicinal chemistry 67 (2) (2024)
Kaixin Ni, Nicolás Montesdeoca, Johannes Karges
Highly cytotoxic Cu(II) terpyridine complexes as chemotherapeutic agents. Dalton transactions (Cambridge, England : 2003) 53 (19) (2024)
Ganghao Liang, Wanqing Cao, Dongsheng Tang, Hanchen Zhang, Yingjie Yu, Jian-Xun Ding, Johannes Karges, Haihua Xiao
Nanomedomics. ACS nano (2024)
Nicolás Montesdeoca, Kaixin Ni, Johannes Karges
Encapsulation of Cu(II) Terpyridine Complexes into Polymeric Nanoparticles for Enhanced Anticancer Therapy. Chemistry (Weinheim an der Bergstrasse, Germany) (2024)
Haobing Wang, Yidan Lai, Dan Li, Johannes Karges, Pingyu Zhang, Huaiyi Huang
Self-Assembly of Erlotinib-Platinum(II) Complexes for Epidermal Growth Factor Receptor-Targeted Photodynamic Therapy. Journal of medicinal chemistry (2024)
Haobing Wang, Yidan Lai, Dan Li, Johannes Karges, Pingyu Zhang, Huaiyi Huang
Self-Assembly of Erlotinib-Platinum(II) Complexes for Epidermal Growth Factor Receptor-Targeted Photodynamic Therapy. Journal of medicinal chemistry 67 (2) (2024)
Tao Feng, Zixin Tang, Johannes Karges, Jun Shu, Kai Xiong, Chengzhi Jin, Yu Chen, Gilles Gasser, Liangnian Ji, Hui Chao
An iridium(iii)-based photosensitizer disrupting the mitochondrial respiratory chain induces ferritinophagy-mediated immunogenic cell death. Chemical science 15 (18) (2024)
Alessia Fennes, Nicolás Montesdeoca, Zisis Papadopoulos, Johannes Karges
Rational design of a red-light absorbing ruthenium polypyridine complex as a photosensitizer for photodynamic therapy. Chemical communications (Cambridge, England) (2024)
Ganghao Liang, Wanqing Cao, Dongsheng Tang, Hanchen Zhang, Yingjie Yu, Jian-Xun Ding, Johannes Karges, Haihua Xiao
Nanomedomics. ACS nano 18 (17) (2024)
Kaixin Ni, Nicolás Montesdeoca, Johannes Karges
Highly cytotoxic Cu(II) terpyridine complexes as chemotherapeutic agents. Dalton transactions (Cambridge, England : 2003) (2024)
Nicolás Montesdeoca, Kaixin Ni, Johannes Karges
Encapsulation of Cu(II) Terpyridine Complexes into Polymeric Nanoparticles for Enhanced Anticancer Therapy. Chemistry (Weinheim an der Bergstrasse, Germany) 30 (48) (2024)
Peng Xie, Qiao Jin, Lingpu Zhang, Hanchen Zhang, Nicolás Montesdeoca, Johannes Karges, Haihua Xiao, Xinzhan Mao, Haiqin Song, Kun Shang
Endowing Pt(IV) with Perfluorocarbon Chains and Human Serum Albumin Encapsulation for Highly Effective Antitumor Chemoimmunotherapy. ACS nano (2024)
Nicolás Montesdeoca, Reema L Borkar, Malaichamy Sathiyendiran, Johannes Karges
Dinuclear Rhenium(I) Tricarbonyl Complexes as Anticancer Drug Candidates. Chemistry (Weinheim an der Bergstrasse, Germany) 30 (32) (2024)
Ganghao Liang, Wanqing Cao, Dongsheng Tang, Hanchen Zhang, Yingjie Yu, Jian-Xun Ding, Johannes Karges, Haihua Xiao
Nanomedomics. ACS nano 18 (17) (2024)
Peng Xie, Qiao Jin, Lingpu Zhang, Hanchen Zhang, Nicolás Montesdeoca, Johannes Karges, Haihua Xiao, Xinzhan Mao, Haiqin Song, Kun Shang
Endowing Pt(IV) with Perfluorocarbon Chains and Human Serum Albumin Encapsulation for Highly Effective Antitumor Chemoimmunotherapy. ACS nano 18 (21) (2024)
Nicolás Montesdeoca, Reema L Borkar, Malaichamy Sathiyendiran, Johannes Karges
Dinuclear Rhenium(I) Tricarbonyl Complexes as Anticancer Drug Candidates. Chemistry (Weinheim an der Bergstrasse, Germany) (2024)
Tao Feng, Zixin Tang, Johannes Karges, Jun Shu, Kai Xiong, Chengzhi Jin, Yu Chen, Gilles Gasser, Liangnian Ji, Hui Chao
An iridium(iii)-based photosensitizer disrupting the mitochondrial respiratory chain induces ferritinophagy-mediated immunogenic cell death. Chemical science 15 (18) (2024)
Robin Vinck, Orsolya Dömötör, Johannes Karges, Marta Jakubaszek, Johanne Seguin, Michael Tharaud, Vincent Guérineau, Kevin Cariou, Nathalie Mignet, Éva A Enyedy, Gilles Gasser
In Situ Bioconjugation of a Maleimide-Functionalized Ruthenium-Based Photosensitizer to Albumin for Photodynamic Therapy. Inorganic chemistry (2023)
Johannes Karges, Seth M Cohen
Rhenium(V) Complexes as Cysteine-Targeting Coordinate Covalent Warheads. Journal of medicinal chemistry (2023)
Johannes Karges, Seth M Cohen
Rhenium(V) Complexes as Cysteine-Targeting Coordinate Covalent Warheads. Journal of medicinal chemistry 66 (4) (2023)
Fangmian Wei, Libing Ke, Siyuan Gao, Johannes Karges, Jinquan Wang, Yu Chen, Liangnian Ji, Hui Chao
In situ oxidative polymerization of platinum(iv) prodrugs in pore-confined spaces of CaCO 3 nanoparticles for cancer chemoimmunotherapy. Chemical science 14 (25) (2023)
Johannes Karges, Seth M Cohen
Rhenium(V) Complexes as Cysteine-Targeting Coordinate Covalent Warheads. Journal of medicinal chemistry 66 (4) (2023)
Johannes Karges, Seth M Cohen
Rhenium(V) Complexes as Cysteine-Targeting Coordinate Covalent Warheads. Journal of medicinal chemistry 66 (4) (2023)
Huiling Zhou, Dongsheng Tang, Yingjie Yu, Lingpu Zhang, Bin Wang, Johannes Karges, Haihua Xiao
Theranostic imaging and multimodal photodynamic therapy and immunotherapy using the mTOR signaling pathway. Nature communications 14 (1) (2023)
Johannes Karges
Encapsulation of Ru(II) Polypyridine Complexes for Tumor-Targeted Anticancer Therapy. BME frontiers 4 (2023)
Johannes Karges, Seth M Cohen
Rhenium(V) Complexes as Cysteine-Targeting Coordinate Covalent Warheads. Journal of medicinal chemistry 66 (4) (2023)
Lingpu Zhang, Nicolás Montesdeoca, Johannes Karges, Haihua Xiao
Immunogenic Cell Death Inducing Metal Complexes for Cancer Therapy. Angewandte Chemie (International ed. in English) (2023)
Johannes Karges, Seth M Cohen
Rhenium(V) Complexes as Cysteine-Targeting Coordinate Covalent Warheads. Journal of medicinal chemistry 66 (4) (2023)
Fangmian Wei, Libing Ke, Siyuan Gao, Johannes Karges, Jinquan Wang, Yu Chen, Liangnian Ji, Hui Chao
In situ oxidative polymerization of platinum(iv) prodrugs in pore-confined spaces of CaCO 3 nanoparticles for cancer chemoimmunotherapy. Chemical science 14 (25) (2023)
Sarah Boumati, Angélique Sour, Valérie Heitz, Johanne Seguin, Gautier Beitz, Yusuke Kaga, Marta Jakubaszek, Johannes Karges, Gilles Gasser, Nathalie Mignet, Bich-Thuy Doan
Three in One: In Vitro and In Vivo Evaluation of Anticancer Activity of a Theranostic Agent that Combines Magnetic Resonance Imaging, Optical Bioimaging, and Photodynamic Therapy Capabilities. ACS applied bio materials (2023)
Fangmian Wei, Libing Ke, Siyuan Gao, Johannes Karges, Jinquan Wang, Yu Chen, Liangnian Ji, Hui Chao
In situ oxidative polymerization of platinum(iv) prodrugs in pore-confined spaces of CaCO 3 nanoparticles for cancer chemoimmunotherapy. Chemical science 14 (25) (2023)
Lili Wang, Johannes Karges, Fangmian Wei, Lina Xie, Zhuoli Chen, Gilles Gasser, Liangnian Ji, Hui Chao
A mitochondria-localized iridium(iii) photosensitizer for two-photon photodynamic immunotherapy against melanoma. Chemical science 14 (6) (2023)
Lili Wang, Johannes Karges, Fangmian Wei, Lina Xie, Zhuoli Chen, Gilles Gasser, Liangnian Ji, Hui Chao
A mitochondria-localized iridium(iii) photosensitizer for two-photon photodynamic immunotherapy against melanoma. Chemical science 14 (6) (2023)
Xiangjie Gao, Guanxiong Lei, Bin Wang, Zhong Deng, Johannes Karges, Haihua Xiao, Donghui Tan
Encapsulation of Platinum Prodrugs into PC7A Polymeric Nanoparticles Combined with Immune Checkpoint Inhibitors for Therapeutically Enhanced Multimodal Chemotherapy and Immunotherapy by Activation of the STING Pathway. Advanced science (Weinheim, Baden-Wurttemberg, Germany) 10 (4) (2022)
Shi Kuang, Fangmian Wei, Johannes Karges, Libing Ke, Kai Xiong, Xinxing Liao, Gilles Gasser, Liangnian Ji, Hui Chao
Photodecaging of a Mitochondria-Localized Iridium(III) Endoperoxide Complex for Two-Photon Photoactivated Therapy under Hypoxia. Journal of the American Chemical Society 144 (9) (2022)
Mingwei Lin, Shanshan Zou, Tingzhen Li, Johannes Karges, Yu Chen, Yukun Zhao, Liangnian Ji, Hui Chao
Chiral rhodium(III)-azobenzene complexes as photoswitchable DNA molecular locks. Chemical communications (Cambridge, England) 58 (27) (2022)
Xiangjie Gao, Guanxiong Lei, Bin Wang, Zhong Deng, Johannes Karges, Haihua Xiao, Donghui Tan
Encapsulation of Platinum Prodrugs into PC7A Polymeric Nanoparticles Combined with Immune Checkpoint Inhibitors for Therapeutically Enhanced Multimodal Chemotherapy and Immunotherapy by Activation of the STING Pathway. Advanced science (Weinheim, Baden-Wurttemberg, Germany) (2022)
Xiangjie Gao, Guanxiong Lei, Bin Wang, Zhong Deng, Johannes Karges, Haihua Xiao, Donghui Tan
Encapsulation of Platinum Prodrugs into PC7A Polymeric Nanoparticles Combined with Immune Checkpoint Inhibitors for Therapeutically Enhanced Multimodal Chemotherapy and Immunotherapy by Activation of the STING Pathway. Advanced science (Weinheim, Baden-Wurttemberg, Germany) 10 (4) (2022)
Ryjul W Stokes, Alysia J Kohlbrand, Hyeonglim Seo, Banumathi Sankaran, Johannes Karges, Seth M Cohen
Carboxylic Acid Isostere Derivatives of Hydroxypyridinones as Core Scaffolds for Influenza Endonuclease Inhibitors. ACS medicinal chemistry letters 14 (1) (2022)
Ryjul W Stokes, Alysia J Kohlbrand, Hyeonglim Seo, Banumathi Sankaran, Johannes Karges, Seth M Cohen
Carboxylic Acid Isostere Derivatives of Hydroxypyridinones as Core Scaffolds for Influenza Endonuclease Inhibitors. ACS medicinal chemistry letters 14 (1) (2022)
Xiangjie Gao, Guanxiong Lei, Bin Wang, Zhong Deng, Johannes Karges, Haihua Xiao, Donghui Tan
Encapsulation of Platinum Prodrugs into PC7A Polymeric Nanoparticles Combined with Immune Checkpoint Inhibitors for Therapeutically Enhanced Multimodal Chemotherapy and Immunotherapy by Activation of the STING Pathway. Advanced science (Weinheim, Baden-Wurttemberg, Germany) 10 (4) (2022)
Moritz K Jackl, Hyeonglim Seo, Johannes Karges, Mark Kalaj, Seth M Cohen
Salicylate metal-binding isosteres as fragments for metalloenzyme inhibition. Chemical science 13 (7) (2022)
Johannes Karges, Miriam A Giardini, Olivier Blacque, Brendon Woodworth, Jair L Siqueira-Neto, Seth M Cohen
Enantioselective inhibition of the SARS-CoV-2 main protease with rhenium(i) picolinic acid complexes. Chemical science 14 (3) (2022)
Dengshuai Wei, Yun Huang, Bin Wang, Lili Ma, Johannes Karges, Haihua Xiao
Photo-Reduction with NIR Light of Nucleus-Targeting Pt IV Nanoparticles for Combined Tumor-Targeted Chemotherapy and Photodynamic Immunotherapy. Angewandte Chemie (International ed. in English) 61 (20) (2022)
Xiangjie Gao, Guanxiong Lei, Bin Wang, Zhong Deng, Johannes Karges, Haihua Xiao, Donghui Tan
Encapsulation of Platinum Prodrugs into PC7A Polymeric Nanoparticles Combined with Immune Checkpoint Inhibitors for Therapeutically Enhanced Multimodal Chemotherapy and Immunotherapy by Activation of the STING Pathway. Advanced science (Weinheim, Baden-Wurttemberg, Germany) 10 (4) (2022)
Ryjul W Stokes, Alysia J Kohlbrand, Hyeonglim Seo, Banumathi Sankaran, Johannes Karges, Seth M Cohen
Carboxylic Acid Isostere Derivatives of Hydroxypyridinones as Core Scaffolds for Influenza Endonuclease Inhibitors. ACS medicinal chemistry letters 14 (1) (2022)
Johannes Karges, Ryjul W Stokes, Seth M Cohen
Computational Prediction of the Binding Pose of Metal-Binding Pharmacophores. ACS medicinal chemistry letters 13 (3) (2022)
Johannes Karges, Miriam A Giardini, Olivier Blacque, Brendon Woodworth, Jair L Siqueira-Neto, Seth M Cohen
Enantioselective inhibition of the SARS-CoV-2 main protease with rhenium(i) picolinic acid complexes. Chemical science 14 (3) (2022)
Johannes Karges, Ryjul W Stokes, Seth M Cohen
Photorelease of a metal-binding pharmacophore from a Ru(II) polypyridine complex. Dalton transactions (Cambridge, England : 2003) 50 (8) (2021)
Robin Vinck, Johannes Karges, Michael Tharaud, Kevin Cariou, Gilles Gasser
Physical, spectroscopic, and biological properties of ruthenium and osmium photosensitizers bearing diversely substituted 4,4'-di(styryl)-2,2'-bipyridine ligands. Dalton transactions (Cambridge, England : 2003) 50 (41) (2021)
Johannes Karges, Seth M Cohen
Metal Complexes as Antiviral Agents for SARS-CoV-2. Chembiochem : a European journal of chemical biology 22 (16) (2021)
Johannes Karges, Diana Díaz-García, Sanjiv Prashar, Santiago Gómez-Ruiz, Gilles Gasser
Ru(II) Polypyridine Complex-Functionalized Mesoporous Silica Nanoparticles as Photosensitizers for Cancer Targeted Photodynamic Therapy. ACS applied bio materials 4 (5) (2021)
Johannes Karges, Ryjul W Stokes, Seth M Cohen
Metal Complexes for Therapeutic Applications. Trends in chemistry 3 (7) (2021)
Maria Gil-Moles, Sebastian Türck, Uttara Basu, Andrea Pettenuzzo, Saurav Bhattacharya, Ananthu Rajan, Xiang Ma, Rolf Büssing, Jessica Wölker, Hilke Burmeister, Henrik Hoffmeister, Pia Schneeberg, Andre Prause, Petra Lippmann, Josephine Kusi-Nimarko, Storm Hassell-Hart, Andrew McGown, Daniel Guest, Yan Lin, Anna Notaro, Robin Vinck, Johannes Karges, Kevin Cariou, Kun Peng, Xue Qin, Xing Wang, Joanna Skiba, Łukasz Szczupak, Konrad Kowalski, Ulrich Schatzschneider, Catherine Hemmert, Heinz Gornitzka, Elena R Milaeva, Alexey A Nazarov, Gilles Gasser, John Spencer, Luca Ronconi, Ulrich Kortz, Jindrich Cinatl, Denisa Bojkova, Ingo Ott
Metallodrug Profiling against SARS-CoV-2 Target Proteins Identifies Highly Potent Inhibitors of the S/ACE2 interaction and the Papain-like Protease PLpro. Chemistry (Weinheim an der Bergstrasse, Germany) (2021)
Johannes Karges, Michael Tharaud, Gilles Gasser
Polymeric Encapsulation of a Ru(II)-Based Photosensitizer for Folate-Targeted Photodynamic Therapy of Drug Resistant Cancers. Journal of medicinal chemistry 64 (8) (2021)
Luke K McKenzie, Marie Flamme, Patrick S Felder, Johannes Karges, Frédéric Bonhomme, Albert Gandioso, Christian Malosse, Gilles Gasser, Marcel R Hollenstein
A ruthenium-oligonucleotide bioconjugated photosensitizing aptamer for cancer cell specific photodynamic therapy. RSC chemical biology 3 (1) (2021)
Hyeonglim Seo, Kathleen E Prosser, Mark Kalaj, Johannes Karges, Benjamin L Dick, Seth M Cohen
Evaluating Metal-Ligand Interactions of Metal-Binding Isosteres Using Model Complexes. Inorganic chemistry 60 (22) (2021)
Johannes Karges
Clinical Development of Metal Complexes as Photosensitizers for Photodynamic Therapy of Cancer. Angewandte Chemie (International ed. in English) (2021)
Johannes Karges, Mark Kalaj, Milan Gembicky, Seth M Cohen
ReI Tricarbonyl Complexes as Coordinate Covalent Inhibitors for the SARS-CoV-2 Main Cysteine Protease. Angewandte Chemie (International ed. in English) 60 (19) (2021)
Kai Xiong, Ying Zhou, Johannes Karges, Kejie Du, Jinchao Shen, Mingwei Lin, Fangmian Wei, Junfeng Kou, Yu Chen, Liangnian Ji, Hui Chao
Autophagy-Dependent Apoptosis Induced by Apoferritin-Cu(II) Nanoparticles in Multidrug-Resistant Colon Cancer Cells. ACS applied materials & interfaces 13 (33) (2021)
Yan Lin, Yih Ching Ong, Sarah Keller, Johannes Karges, Rafika Bouchene, Eric Manoury, Olivier Blacque, Joachim Müller, Nicoleta Anghel, Andrew Hemphill, Cécile Häberli, Aya C Taki, Robin B Gasser, Kevin Cariou, Jennifer Keiser, Gilles Gasser
Synthesis, characterization and antiparasitic activity of organometallic derivatives of the anthelmintic drug albendazole. Dalton transactions (Cambridge, England : 2003) 49 (20) (2021)
Johannes Karges, Hyeonglim Seo, Seth M Cohen
Synthesis of tetranuclear rhenium(I) tricarbonyl metallacycles. Dalton transactions (Cambridge, England : 2003) 50 (44) (2021)
Johannes Karges, Hui Chao, Gilles Gasser
Critical discussion of the applications of metal complexes for 2-photon photodynamic therapy. Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 25 (8) (2020)
Johannes Karges, Jia Li, Leli Zeng, Hui Chao, Gilles Gasser
Polymeric Encapsulation of a Ruthenium Polypyridine Complex for Tumor Targeted One- and Two-Photon Photodynamic Therapy. ACS applied materials & interfaces 12 (49) (2020)
Johannes Karges
Combining Inorganic Chemistry and Biology: The Underestimated Potential of Metal Complexes in Medicine. Chembiochem : a European journal of chemical biology 21 (21) (2020)
Johannes Karges, Shi Kuang, Yih Ching Ong, Hui Chao, Gilles Gasser
One- and Two-Photon Phototherapeutic Effects of RuII Polypyridine Complexes in the Hypoxic Centre of Large Multicellular Tumor Spheroids and Tumor-Bearing Mice*. Chemistry (Weinheim an der Bergstrasse, Germany) 27 (1) (2020)
Johannes Karges, Thirumal Yempala, Mickaël Tharaud, Dan Gibson, Gilles Gasser
A Multi-action and Multi-target RuII -PtIV Conjugate Combining Cancer-Activated Chemotherapy and Photodynamic Therapy to Overcome Drug Resistant Cancers. Angewandte Chemie (International ed. in English) 59 (18) (2020)
Johannes Karges, Shi Kuang, Federica Maschietto, Olivier Blacque, Ilaria Ciofini, Hui Chao, Gilles Gasser
Rationally designed ruthenium complexes for 1- and 2-photon photodynamic therapy. Nature communications 11 (1) (2020)
Nancy Soliman, Luke K McKenzie, Johannes Karges, Emilie Bertrand, Michael Tharaud, Marta Jakubaszek, Vincent Guérineau, Bruno Goud, Marcel R Hollenstein, Gilles Gasser, Christophe M Thomas
Ruthenium-initiated polymerization of lactide: a route to remarkable cellular uptake for photodynamic therapy of cancer. Chemical science 11 (10) (2020)
Anna K Renfrew, Johannes Karges, Rosario Scopelliti, Felix D Bobbink, Patrycja Nowak-Sliwinska, Gilles Gasser, Paul J Dyson
Towards Light-Activated Ruthenium-Arene (RAPTA-Type) Prodrug Candidates. Chembiochem : a European journal of chemical biology 20 (22) (2019)
Johannes Karges, Marta Jakubaszek, Cristina Mari, Kristof Zarschler, Bruno Goud, Holger Stephan, Gilles Gasser
Synthesis and Characterization of an Epidermal Growth Factor Receptor-Selective RuII Polypyridyl-Nanobody Conjugate as a Photosensitizer for Photodynamic Therapy. Chembiochem : a European journal of chemical biology 21 (4) (2019)

Johannes Karges.css-eqlu8i{font-size:small;padding-left:4px;}

Publication Activity (10 Years)

Top Topics

Top Venues

Johannes Karges