Anti-GD2 Antibodies Conjugated to IL15 and IL21 Mediate Potent Antitumor Cytotoxicity against Neuroblastoma.

Rosa Nguyen Xiyuan ZhangMing SunShahroze AbbasCharlie SeibertMichael C Kelly Jack F Shern Carol J Thiele

Published in: Clinical cancer research : an official journal of the American Association for Cancer Research (2022)

Hu14.18-IL15 and Hu14.18-IL21 exhibit robust preclinical activity, warranting further consideration for clinical testing in patients with GD2-expressing neuroblastoma.

Keyphrases

stem cells
photodynamic therapy
bone marrow
cell therapy
mesenchymal stem cells
wild type