Jack F Shern (Jack Shern, John Shern)

Publication Activity (10 Years)

Years Active: 2019-2024
Publications (10 Years): 34

Top Topics

Peripheral Nerve

Top Venues

Clinical cancer research : an official journal of the American Association for Cancer Research

medRxiv : the preprint server for health sciences

Cancer research

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

This page only lists publications with an associated author ORCID identifier.

Publications

Yong Yean Kim, Berkley E Gryder, Ranuka Sinniah, Megan L Peach, Jack F Shern, Abdalla Abdelmaksoud, Silvia Pomella, Girma M Woldemichael, Benjamin Z Stanton, David Milewski, Joseph J Barchi, John S Schneekloth, Raj Chari, Joshua T Kowalczyk, Shilpa R Shenoy, Jason R Evans, Young K Song, Chaoyu Wang, Xinyu Wen, Hsien-Chao Chou, Vineela Gangalapudi, Dominic Esposito, Jane Jones, Lauren Procter, Maura O'Neill, Lisa M Miller Jenkins, Nadya I Tarasova, Jun S Wei, James B McMahon, Barry R Oâ Keefe, Robert G Hawley, Javed Khan
KDM3B inhibitors disrupt the oncogenic activity of PAX3-FOXO1 in fusion-positive rhabdomyosarcoma. Nature communications 15 (1) (2024)
Alanna J Church, Claire E Wakefield, Kate Hetherington, Jack F Shern
Promise and Perils of Precision Oncology for Patients With Pediatric and Young Adult Sarcomas. American Society of Clinical Oncology educational book. American Society of Clinical Oncology. Annual Meeting 44 (3) (2024)
Yong Yean Kim, Berkley E Gryder, Ranuka Sinniah, Megan L Peach, Jack F Shern, Abdalla Abdelmaksoud, Silvia Pomella, Girma M Woldemichael, Benjamin Z Stanton, David Milewski, Joseph J Barchi, John S Schneekloth, Raj Chari, Joshua T Kowalczyk, Shilpa R Shenoy, Jason R Evans, Young K Song, Chaoyu Wang, Xinyu Wen, Hsien-Chao Chou, Vineela Gangalapudi, Dominic Esposito, Jane Jones, Lauren Procter, Maura O'Neill, Lisa M Miller Jenkins, Nadya I Tarasova, Jun S Wei, James B McMahon, Barry R Oâ Keefe, Robert G Hawley, Javed Khan
KDM3B inhibitors disrupt the oncogenic activity of PAX3-FOXO1 in fusion-positive rhabdomyosarcoma. Nature communications 15 (1) (2024)
Yong Yean Kim, Berkley E Gryder, Ranuka Sinniah, Megan L Peach, Jack F Shern, Abdalla Abdelmaksoud, Silvia Pomella, Girma M Woldemichael, Benjamin Z Stanton, David Milewski, Joseph J Barchi, John S Schneekloth, Raj Chari, Joshua T Kowalczyk, Shilpa R Shenoy, Jason R Evans, Young K Song, Chaoyu Wang, Xinyu Wen, Hsien-Chao Chou, Vineela Gangalapudi, Dominic Esposito, Jane Jones, Lauren Procter, Maura O'Neill, Lisa M Miller Jenkins, Nadya I Tarasova, Jun S Wei, James B McMahon, Barry R Oâ Keefe, Robert G Hawley, Javed Khan
KDM3B inhibitors disrupt the oncogenic activity of PAX3-FOXO1 in fusion-positive rhabdomyosarcoma. Nature communications 15 (1) (2024)
R Taylor Sundby, Jeffrey J Szymanski, Alexander Pan, Paul A Jones, Sana Z Mahmood, Olivia H Reid, Divya Srihari, Amy E Armstrong, Stacey Chamberlain, Sanita Burgic, Kara Weekley, Béga Murray, Sneh Patel, Faridi Qaium, Andrea N Lucas, Margaret Fagan, Anne Dufek, Christian F Meyer, Natalie B Collins, Christine A Pratilas, Eva Dombi, Andrea M Gross, Ae Rang Kim, John S A Chrisinger, Carina A Dehner, Brigitte C Widemann, Angela C Hirbe, Aadel A Chaudhuri, Jack F Shern
Early detection of malignant and pre-malignant peripheral nerve tumors using cell-free DNA fragmentomics. Clinical cancer research : an official journal of the American Association for Cancer Research (2024)
R Taylor Sundby, Jeffrey J Szymanski, Alexander Pan, Paul A Jones, Sana Z Mahmood, Olivia H Reid, Divya Srihari, Amy E Armstrong, Stacey Chamberlain, Sanita Burgic, Kara Weekley, Béga Murray, Sneh Patel, Faridi Qaium, Andrea N Lucas, Margaret Fagan, Anne Dufek, Christian F Meyer, Natalie B Collins, Christine A Pratilas, Eva Dombi, Andrea M Gross, Ae Rang Kim, John S A Chrisinger, Carina A Dehner, Brigitte C Widemann, Angela C Hirbe, Aadel A Chaudhuri, Jack F Shern
Early detection of malignant and pre-malignant peripheral nerve tumors using cell-free DNA fragmentomics. medRxiv : the preprint server for health sciences (2024)
R Taylor Sundby, Jeffrey J Szymanski, Alexander Pan, Paul A Jones, Sana Z Mahmood, Olivia H Reid, Divya Srihari, Amy E Armstrong, Stacey Chamberlain, Sanita Burgic, Kara Weekley, Béga Murray, Sneh Patel, Faridi Qaium, Andrea N Lucas, Margaret Fagan, Anne Dufek, Christian F Meyer, Natalie B Collins, Christine A Pratilas, Eva Dombi, Andrea M Gross, Ae Rang Kim, John S A Chrisinger, Carina A Dehner, Brigitte C Widemann, Angela C Hirbe, Aadel A Chaudhuri, Jack F Shern
Early detection of malignant and pre-malignant peripheral nerve tumors using cell-free DNA fragmentomics. medRxiv : the preprint server for health sciences (2024)
R Taylor Sundby, Jeffrey J Szymanski, Alexander Pan, Paul A Jones, Sana Z Mahmood, Olivia H Reid, Divya Srihari, Amy E Armstrong, Stacey Chamberlain, Sanita Burgic, Kara Weekley, Béga Murray, Sneh Patel, Faridi Qaium, Andrea N Lucas, Margaret Fagan, Anne Dufek, Christian F Meyer, Natalie B Collins, Christine A Pratilas, Eva Dombi, Andrea M Gross, Ae Rang Kim, John S A Chrisinger, Carina A Dehner, Brigitte C Widemann, Angela C Hirbe, Aadel A Chaudhuri, Jack F Shern
Early detection of malignant and pre-malignant peripheral nerve tumors using cell-free DNA fragmentomics. medRxiv : the preprint server for health sciences (2024)
R Taylor Sundby, Jeffrey J Szymanski, Alexander Pan, Paul A Jones, Sana Z Mahmood, Olivia H Reid, Divya Srihari, Amy E Armstrong, Stacey Chamberlain, Sanita Burgic, Kara Weekley, Béga Murray, Sneh Patel, Andrea N Lucas, Margaret Fagan, Anne Dufek, Christian F Meyer, Natalie B Collins, Brian A Van Tine, Eva Dombi, Andrea M Gross, Ae Rang Kim, John S A Chrisinger, Carina A Dehner, Brigitte C Widemann, Angela C Hirbe, Aadel A Chaudhuri, Jack F Shern
Early detection of malignant and pre-malignant peripheral nerve tumors using cell-free DNA fragmentomics. medRxiv : the preprint server for health sciences (2024)
R Taylor Sundby, Jeffrey J Szymanski, Alexander Pan, Paul A Jones, Sana Z Mahmood, Olivia H Reid, Divya Srihari, Amy E Armstrong, Stacey Chamberlain, Sanita Burgic, Kara Weekley, Béga Murray, Sneh Patel, Faridi Qaium, Andrea N Lucas, Margaret Fagan, Anne Dufek, Christian F Meyer, Natalie B Collins, Christine A Pratilas, Eva Dombi, Andrea M Gross, Ae Rang Kim, John S A Chrisinger, Carina A Dehner, Brigitte C Widemann, Angela C Hirbe, Aadel A Chaudhuri, Jack F Shern
Early detection of malignant and pre-malignant peripheral nerve tumors using cell-free DNA fragmentomics. Clinical cancer research : an official journal of the American Association for Cancer Research (2024)
Yong Yean Kim, Berkley E Gryder, Ranuka Sinniah, Megan L Peach, Jack F Shern, Abdalla Abdelmaksoud, Silvia Pomella, Girma M Woldemichael, Benjamin Z Stanton, David Milewski, Joseph J Barchi, John S Schneekloth, Raj Chari, Joshua T Kowalczyk, Shilpa R Shenoy, Jason R Evans, Young K Song, Chaoyu Wang, Xinyu Wen, Hsien-Chao Chou, Vineela Gangalapudi, Dominic Esposito, Jane Jones, Lauren Procter, Maura O'Neill, Lisa M Miller Jenkins, Nadya I Tarasova, Jun S Wei, James B McMahon, Barry R Oâ Keefe, Robert G Hawley, Javed Khan
KDM3B inhibitors disrupt the oncogenic activity of PAX3-FOXO1 in fusion-positive rhabdomyosarcoma. Nature communications 15 (1) (2024)
R Taylor Sundby, Jeffrey J Szymanski, Alexander Pan, Paul A Jones, Sana Z Mahmood, Olivia H Reid, Divya Srihari, Amy E Armstrong, Stacey Chamberlain, Sanita Burgic, Kara Weekley, Béga Murray, Sneh Patel, Faridi Qaium, Andrea N Lucas, Margaret Fagan, Anne Dufek, Christian F Meyer, Natalie B Collins, Brian A Van Tine, Christine A Pratilas, Eva Dombi, Andrea M Gross, Ae Rang Kim, John S A Chrisinger, Carina A Dehner, Brigitte C Widemann, Angela C Hirbe, Aadel A Chaudhuri, Jack F Shern
Early detection of malignant and pre-malignant peripheral nerve tumors using cell-free DNA fragmentomics. medRxiv : the preprint server for health sciences (2024)
R Taylor Sundby, Jeffrey J Szymanski, Alexander Pan, Paul A Jones, Sana Z Mahmood, Olivia H Reid, Divya Srihari, Amy E Armstrong, Stacey Chamberlain, Sanita Burgic, Kara Weekley, Béga Murray, Sneh Patel, Faridi Qaium, Andrea N Lucas, Margaret Fagan, Anne Dufek, Christian F Meyer, Natalie B Collins, Brian A Van Tine, Christine A Pratilas, Eva Dombi, Andrea M Gross, Ae Rang Kim, John S A Chrisinger, Carina A Dehner, Brigitte C Widemann, Angela C Hirbe, Aadel A Chaudhuri, Jack F Shern
Early detection of malignant and pre-malignant peripheral nerve tumors using cell-free DNA fragmentomics. medRxiv : the preprint server for health sciences (2024)
R Taylor Sundby, Jeffrey J Szymanski, Alexander Pan, Paul A Jones, Sana Z Mahmood, Olivia H Reid, Divya Srihari, Amy E Armstrong, Stacey Chamberlain, Sanita Burgic, Kara Weekley, Béga Murray, Sneh Patel, Faridi Qaium, Andrea N Lucas, Margaret Fagan, Anne Dufek, Christian F Meyer, Natalie B Collins, Christine A Pratilas, Eva Dombi, Andrea M Gross, Ae Rang Kim, John S A Chrisinger, Carina A Dehner, Brigitte C Widemann, Angela C Hirbe, Aadel A Chaudhuri, Jack F Shern
Early detection of malignant and pre-malignant peripheral nerve tumors using cell-free DNA fragmentomics. medRxiv : the preprint server for health sciences (2024)
Man Xu, Ming Sun, Xiyuan Zhang, Rosa Nguyen, Haiyan Lei, Jack F Shern, Carol J Thiele, Zhihui Liu
HAND2 Assists MYCN Enhancer Invasion to Regulate a Noradrenergic Neuroblastoma Phenotype. Cancer research 83 (5) (2023)
Grace B McKay-Corkum, Victor J Collins, Choh Yeung, Takeshi Ito, Sameer H Issaq, David O Holland, Ksenia Vulikh, Yiping Zhang, Unsun Lee, Haiyan Lei, Arnulfo Mendoza, Jack F Shern, Marielle E Yohe, Kazutoshi Yamamoto, Kelli M Wilson, Jiuping Ji, Baktiar O Karim, Craig J Thomas, Murali C Krishna, Leonard M Neckers, Christine M Heske
Inhibition of NAD+-dependent metabolic processes induces cellular necrosis and tumor regression in rhabdomyosarcoma models. Clinical cancer research : an official journal of the American Association for Cancer Research (2023)
Man Xu, Ming Sun, Xiyuan Zhang, Rosa Nguyen, Haiyan Lei, Jack F Shern, Carol J Thiele, Zhihui Liu
HAND2 Assists MYCN Enhancer Invasion to Regulate a Noradrenergic Neuroblastoma Phenotype. Cancer research 83 (5) (2023)
Samuel Abbou, Kelly S Klega, Junko Tsuji, Mohammad Tanhaemami, David C Hall, Donald A Barkauskas, Mark D Krailo, Carrie Cibulskis, Anwesha Nag, Aaron R Thorner, Samuel Pollock, Alma Imamovic, Jack F Shern, Steven G DuBois, Rajkumar Venkatramani, Douglas S Hawkins, Brian D Crompton
Circulating Tumor DNA Is Prognostic in Intermediate-Risk Rhabdomyosarcoma: A Report From the Children's Oncology Group. Journal of clinical oncology : official journal of the American Society of Clinical Oncology (2023)
Joseph A Flores-Toro, Subhashini Jagu, Gregory T Armstrong, David F Arons, Gregory J Aune, Stephen J Chanock, Douglas S Hawkins, Allison P Heath, Lee J Helman, Katherine A Janeway, Jason E Levine, Ellyn Miller, Lynne Penberthy, Charles W M Roberts, Eve R Shalley, Jack F Shern, Malcolm A Smith, Louis M Staudt, Samuel L Volchenboum, Jinghui Zhang, Jean Claude Zenklusen, Douglas R Lowy, Norman E Sharpless, Jaime M Guidry Auvil, Anthony R Kerlavage, Brigitte C Widemann, Gregory H Reaman, Warren A Kibbe, James H Doroshow, null null, null null
The Childhood Cancer Data Initiative: Using the Power of Data to Learn From and Improve Outcomes for Every Child and Young Adult With Pediatric Cancer. Journal of clinical oncology : official journal of the American Society of Clinical Oncology (2023)
Samuel Abbou, Kelly S Klega, Junko Tsuji, Mohammad Tanhaemami, David C Hall, Donald A Barkauskas, Mark D Krailo, Carrie Cibulskis, Anwesha Nag, Aaron R Thorner, Samuel Pollock, Alma Imamovic, Jack F Shern, Steven G DuBois, Rajkumar Venkatramani, Douglas S Hawkins, Brian D Crompton
Circulating Tumor DNA Is Prognostic in Intermediate-Risk Rhabdomyosarcoma: A Report From the Children's Oncology Group. Journal of clinical oncology : official journal of the American Society of Clinical Oncology (2023)
Man Xu, Ming Sun, Xiyuan Zhang, Rosa Nguyen, Haiyan Lei, Jack F Shern, Carol J Thiele, Zhihui Liu
HAND2 Assists MYCN Enhancer Invasion to Regulate a Noradrenergic Neuroblastoma Phenotype. Cancer research 83 (5) (2023)
Srivandana Akshintala, R Taylor Sundby, Donna B Bernstein, John W Glod, Rosandra N Kaplan, Marielle E Yohe, Andrea M Gross, Joanne Derdak, Haiyan Lei, Alexander Pan, Eva Dombi, Isabel Palacio-Yance, Kailey R Herrera, Markku M Miettinen, Helen X Chen, Seth M Steinberg, Lee J Helman, Leo Mascarenhas, Brigitte C Widemann, Fariba Navid, Jack F Shern, Christine M Heske
Phase I trial of ganitumab plus dasatinib to cotarget the insulin-like growth factor 1 receptor and Src family kinase YES in rhabdomyosarcoma. Clinical cancer research : an official journal of the American Association for Cancer Research (2023)
Carina A Dehner, Robert C Bell, Yang Cao, Kevin He, John S A Chrisinger, Amy E Armstrong, Marielle E Yohe, Jack F Shern, Angela C Hirbe
Loss of Chromosome 3q Is a Prognostic Marker in Fusion-Negative Rhabdomyosarcoma. JCO precision oncology 7 (2023)
Rosa Nguyen, Ekaterina Doubrovina, Charlotte M Mousset, Benjamin Y Jin, Reona Okada, Xiyuan Zhang, Arina Clavel, Jeyshka M Reyes-González, Vadim Dyomin, Louis Diaz, Ling Zhang, Shahroze Abbas, Ming Sun, Chao-Ming Hsieh, Mitchell Ho, Jack F Shern, James L Gulley, Christian S Hinrichs
Cooperative armoring of CAR and TCR T-cells by T cell-restricted IL-15 and IL-21 universally enhances solid tumor efficacy. Clinical cancer research : an official journal of the American Association for Cancer Research (2023)
Man Xu, Ming Sun, Xiyuan Zhang, Rosa Nguyen, Haiyan Lei, Jack F Shern, Carol J Thiele, Zhihui Liu
HAND2 assists MYCN enhancer invasion to regulate a noradrenergic neuroblastoma phenotype. Cancer research (2023)
David Milewski, Hyun Jung, G Thomas Brown, Yanling Liu, Ben Somerville, Curtis Lisle, Marc Ladanyi, Erin R Rudzinski, Hyoyoung Choo-Wosoba, Donald A Barkauskas, Tammy Lo, David C Hall, Corinne M Linardic, Jun S Wei, Hsien-Chao Chou, Stephen X Skapek, Rajkumar Venkatramani, Peter Karl Bode, Seth M Steinberg, George Zaki, Igor B Kuznetsov, Douglas S Hawkins, Jack F Shern, Jack Collins, Javed Khan
Predicting Molecular Subtype and Survival of Rhabdomyosarcoma Patients using Deep Learning of H&E Images: A Report from the Children's Oncology Group. Clinical cancer research : an official journal of the American Association for Cancer Research (2022)
Rosa Nguyen, Xiyuan Zhang, Ming Sun, Shahroze Abbas, Charlie Seibert, Michael C Kelly, Jack F Shern, Carol J Thiele
Anti-GD2 Antibodies Conjugated to IL15 and IL21 Mediate Potent Antitumor Cytotoxicity against Neuroblastoma. Clinical cancer research : an official journal of the American Association for Cancer Research 28 (17) (2022)
Zhihui Liu, Xiyuan Zhang, Man Xu, Haiyan Lei, Jack F Shern, Carol J Thiele
Loss of CASZ1 tumor suppressor linked to oncogenic subversion of neuroblastoma core regulatory circuitry. Cell death & disease 13 (10) (2022)
John A Ligon, R Taylor Sundby, Mary Frances Wedekind Malone, Fernanda I Arnaldez, Jaydira Del Rivero, Lori S Wiener, Ramaprasad Srinivasan, Melissa Spencer, Amanda Carbonell, Haiyan Lei, Jack F Shern, Seth M Steinberg, William Douglas Figg, Cody J Peer, Sara M Zimmerman, Josquin Moraly, Xia Xu, Stephen Fox, King Chan, Michael I Barbato, Thorkell Andressen, Naomi Taylor, Karel Pacak, J Keith Killian, Eva Dombi, W Marston Linehan, Markku M Miettinen, Richard L Piekarz, Lee J Helman, Paul S Meltzer, Brigitte C Widemann, John W Glod
A Phase II Trial of Guadecitabine in Children and Adults with SDH-Deficient GIST, Pheochromocytoma, Paraganglioma, and HLRCC-associated Renal Cell Carcinoma. Clinical cancer research : an official journal of the American Association for Cancer Research (2022)
Katie E Hebron, Xiaolin Wan, Jacob S Roth, David J Liewehr, Nancy E Sealover, William J E Frye, Angela Kim, Stacey Stauffer, Olivia L Perkins, Wenyue Sun, Kristine A Isanogle, Christina M Robinson, Amy James, Parirokh Awasthi, Priya Shankarappa, Xiaoling Luo, Haiyan Lei, Donna Butcher, Roberta Smith, Elijah F Edmondson, Jin-Qiu Chen, Noemi Kedei, Cody J Peer, Jack F Shern, William Douglas Figg, Lu Chen, Matthew D Hall, Simone Difilippantonio, Frederic G Barr, Robert L Kortum, Robert W Robey, Angelina V Vaseva, Javed Khan, Marielle E Yohe
The combination of trametinib and ganitumab is effective in RAS-mutated PAX-fusion negative rhabdomyosarcoma models. Clinical cancer research : an official journal of the American Association for Cancer Research (2022)
Jack F Shern, Joanna L Selfe, Elisa Izquierdo, Rajesh Patidar, Hsien-Chao Chou, Young K Song, Marielle E Yohe, Sivasish Sindiri, Jun S Wei, Xinyu Wen, Erin R Rudzinski, Donald A Barkauskas, Tammy Lo, David C Hall, Corinne M Linardic, Debbie Hughes, Sabri Jamal, Meriel Jenney, Julia C Chisholm, Rebecca Brown, Kristine Jones, Belynda D Hicks, Paola Angelini, Sally L George, Louis Chesler, Michael Hubank, Anna Kelsey, Susanne Andrea Gatz, Stephen X Skapek, Douglas S Hawkins, Janet M Shipley, Javed Khan
Genomic Classification and Clinical Outcome in Rhabdomyosarcoma: A Report From an International Consortium. Journal of clinical oncology : official journal of the American Society of Clinical Oncology 39 (26) (2021)
Jeffrey J Szymanski, R Taylor Sundby, Paul A Jones, Divya Srihari, Noah J Earland, Peter K Harris, Wenjia Feng, Faridi Qaium, Haiyan Lei, David Roberts, Michele Landeau, Jamie Bell, Yi Huang, Leah Hoffman, Melissa Spencer, Matthew B Spraker, Li Ding, Brigitte C Widemann, Jack F Shern, Angela C Hirbe, Aadel A Chaudhuri
Cell-free DNA ultra-low-pass whole genome sequencing to distinguish malignant peripheral nerve sheath tumor (MPNST) from its benign precursor lesion: A cross-sectional study. PLoS medicine 18 (8) (2021)
Sneha Ramakrishna, Steven L Highfill, Zachary Walsh, Sang M Nguyen, Haiyan Lei, Jack F Shern, Haiying Qin, Ira L Kraft, Maryalice Stetler-Stevenson, Constance M Yuan, Jennifer D Hwang, Yang Feng, Zhongyu Zhu, Dimiter Dimitrov, Nirali N Shah, Terry J Fry
Modulation of Target Antigen Density Improves CAR T-cell Functionality and Persistence. Clinical cancer research : an official journal of the American Association for Cancer Research 25 (17) (2019)
Choh Yeung, Anna E Gibson, Sameer H Issaq, Nobu Oshima, Joshua T Baumgart, Leah D Edessa, Ganesha Rai, Daniel J Urban, Michelle S Johnson, Gloria A Benavides, Giuseppe L Squadrito, Marielle E Yohe, Haiyan Lei, Sandy Eldridge, John Hamre, Tyrone Dowdy, Victor Ruiz-Rodado, Adrian Lita, Arnulfo Mendoza, Jack F Shern, Mioara Larion, Lee J Helman, Gordon M Stott, Murali C Krishna, Matthew D Hall, Victor Darley-Usmar, Leonard M Neckers, Christine M Heske
Targeting Glycolysis through Inhibition of Lactate Dehydrogenase Impairs Tumor Growth in Preclinical Models of Ewing Sarcoma. Cancer research 79 (19) (2019)