Psidium guajava L. leaf extract inhibits adipocyte differentiation and improves insulin sensitivity in 3T3-L1 cells.

Esther Choi Seoyoung Baek Kuanglim Baek Hye-Kyeong Kim

Published in: Nutrition research and practice (2021)

The results show that GLE inhibits adipogenesis and improves adipocyte function by reducing basal lipolysis and increasing insulin-stimulated glucose uptake in adipocytes, which can be partly associated with antidiabetic effects of guava leaves.

Keyphrases

adipose tissue
insulin resistance
induced apoptosis
type diabetes
fatty acid
cell cycle arrest
high fat diet induced
blood glucose
cell death
metabolic syndrome
signaling pathway
oxidative stress
pi k akt
weight loss