Docosahexaenoic acid mechanisms of action on the bovine oocyte-cumulus complex.

Sébastien ElisMouhamad OseikriaAnais Vitorino CarvalhoPriscila Silvana BertevelloEmilie CorbinAna-Paula Teixeira-GomesJérôme LecardonnelCatherine ArchillaVéronique DuranthonValérie LabasSvetlana Uzbekova

Published in: Journal of ovarian research (2017)

In conclusion, we suggested that low dose of DHA (1 μM) during IVM might activate regulatory mechanisms without evident effect on gene expression and lipid content in oocyte-cumulus complexes, likely through signaling pathways which need to be elucidated in further studies.

Keyphrases

gene expression
low dose
fatty acid
signaling pathway
dna methylation
high dose
transcription factor
pi k akt
epithelial mesenchymal transition
oxidative stress