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Keratin-positive fibrotic extraskeletal myxoid chondrosarcoma: a close mimic of myoepithelial tumour.

Hirokazu SuginoShintaro IwataKaishi SatomiTaisuke MoriSumihito NobusawaToshiteru NagashimaYuko MatsushitaYasushi YatabeKoichi IchimuraAkira KawaiAkihiko Yoshida
Published in: Histopathology (2023)
We identified a small subset of EMCs characterised by keratin expression and prominent stromal fibrosis. This histological pattern must be recognised in the differential diagnosis of myoepithelial tumours because misclassification may lead to the erroneous prediction of tumour behaviour and may alter patient management. NR4A3 genetic analysis should be considered even in the face of keratin expression and prominent stromal fibrosis.
Keyphrases
  • poor prognosis
  • bone marrow
  • binding protein
  • systemic sclerosis
  • idiopathic pulmonary fibrosis
  • liver fibrosis