Enterocolic increase of cannabinoid receptor type 1 and type 2 and clinical improvement after probiotic administration in dogs with chronic signs of colonic dysmotility without mucosal inflammatory changes.

Giacomo RossiGiorgia GioacchiniGraziano PengoJan S SuchodolskiAlbert E JergensKarin AllenspachAlessandra GavazzaSilvia ScarponaSara BerardiLivio GalosiGabrio BassottiMatteo Cerquetella

Published in: Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society (2019)

Our results suggest that probiotic administration can reduce signs of colonic dysmotility, possibly due to microbiota modulation and epithelial cell receptor-mediated signaling in intestinal mucosa.

Keyphrases

ulcerative colitis
bacillus subtilis
oxidative stress
lactic acid
binding protein