Trial of Roflumilast Cream for Chronic Plaque Psoriasis.

Mark G LebwohlKim A PappLinda Stein GoldMelinda J GooderhamLeon H KircikZoe D DraelosSteven E KempersMathew ZirwasKathleen SmithDavid W OsborneMarie-Louise TrotmanLynn NavaleCharlotte MerrittDavid R BerkHoward Welgusnull null

Published in: The New England journal of medicine (2020)

Roflumilast cream administered once daily to affected areas of psoriasis was superior to vehicle cream in leading to a state of clear or almost clear at 6 weeks. Longer and larger trials are needed to determine the durability and safety of roflumilast in psoriasis. (Funded by Arcutis Biotherapeutics; ARQ-151 201 ClinicalTrials.gov number, NCT03638258.).

Keyphrases

atopic dermatitis
clinical trial
coronary artery disease
study protocol
physical activity
phase iii
randomized controlled trial
hidradenitis suppurativa