Molecular determinants of lipid droplet subpopulations and their fates.

Distinct pools of lipid droplets (LDs) exist in individual cells and are demarcated both by their unique proteomes and lipid compositions. Focusing on yeast-based work, we briefly review the state of understanding of LD subsets, and how specific proteins can dictate their identities and fates through lipophagy and lipolysis-mediated turnover.