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Using a limited sampling strategy to investigate the interindividual pharmacokinetic variability in metformin: A large prospective trial.

Ida KuhlmannSidsel Arnspang PedersenPeter Skov EsbechTore Bjerregaard StageMette Marie Hougaard ChristensenFlemming Nielsen
Published in: British journal of clinical pharmacology (2020)
This study further supports the use of the 2-point LSS algorithm in large pharmacokinetic trials.
Keyphrases
  • machine learning
  • study protocol
  • clinical trial
  • deep learning
  • randomized controlled trial
  • open label
  • double blind