Safety and efficacy of Injection of Human Placenta Mesenchymal Stem Cells Derived Exosomes for treatment of complex perianal Fistula in non-Crohn's cases: Clinical trial phase I.
Haleh PakAlireza HadizadehAsieh Heirani-TabasiMasoud SoleimaniReza Akbari AsbaghMohammad Sadegh FazeliAlireza KazemeiniAmir KeshvariMohammad Reza KeramatiFaezeh SalahshourHengameh NazariSeyed Mohsen Ahmadi TaftiBehnam BehboudiPublished in: Journal of gastroenterology and hepatology (2023)
Administration of exosomes isolated from MSCs demonstrates safety and a satisfactory therapeutic effect in treatment complex perianal fistulae therefore it can be a candidate for future studies and might play a significant role in treatment.