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Two intestinal microbiota-derived metabolites, deoxycholic acid and butyrate, synergize to enhance host defense peptide synthesis and alleviate necrotic enteritis.

Dohyung M KimJing LiuMelanie A WhitmoreIsabel TobinZijun ZhaoGuolong Zhang
Published in: Journal of animal science and biotechnology (2024)
DCA synergizes with NaB to induce HDP and claudin-1 expression and enhance NE resistance, with potential for further development as cost-effective antibiotic alternatives.
Keyphrases
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