Oral cancers preceded by Proliferative Verrucous Leukoplakia exhibit distinctive molecular features.
Alejandro Herreros-PomaresDavid HervásLeticia BaganAlex ProañoDiana GarciaJuan SandovalJosé Vicente BagánPublished in: Oral diseases (2023)
PVL-OSCC patients presented lower expression of cancer-related genes. Hypermethylation of the promoter region of many genes was also noticed, indicating that DNA methylation could be a regulatory mechanism.
Keyphrases
- dna methylation
- end stage renal disease
- genome wide
- gene expression
- transcription factor
- ejection fraction
- chronic kidney disease
- newly diagnosed
- poor prognosis
- papillary thyroid
- peritoneal dialysis
- prognostic factors
- squamous cell carcinoma
- patient reported outcomes
- binding protein
- squamous cell
- young adults
- patient reported