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[Methods of surgical reconstruction of the conjunctiva].

D A KrivolapovaAndrey Yurevich AndreevE O OsidakE A Budnikova
Published in: Vestnik oftalmologii (2024)
Reconstruction of the conjunctiva is required for restoration of damaged ocular surface and is an essential part of that process. Traumas, chemical and thermal burns, multiple surgical intervention can seriously damage the integrity of conjunctival tissue and promote the growth of fibrous tissue, scarring of contractures and their shortening, as well as other complications such as trichiasis, erosion and ulcers on the cornea. When a larger area is affected, there may not be enough donor tissue to replace the defect, in which case the tissue grafts are required to be large enough. Modern modifications of surgical techniques and the continued development of tissue engineering, as well as advancements in stem cell research offer promising novel alternatives for solution of those problems. This article reviews the existing surgical methods of conjunctival reconstruction.
Keyphrases
  • stem cells
  • tissue engineering
  • randomized controlled trial
  • systematic review
  • mesenchymal stem cells
  • bone marrow