Direct oral anticoagulants versus vitamin K antagonists in patients with atrial fibrillation on chronic hemodialysis: a meta-analysis of randomized controlled trials.
Denilsa D P NavalhaNicole FelixAlleh NogueiraMariana ClementeAlice D MarinhoRafael Oliva Morgado FerreiraEric PasqualottoCaroline Serafim DagostinLuis Cláudio Santos PintoGilson C FernandesPublished in: International urology and nephrology (2023)
In this meta-analysis of three RCTs, no significant difference was observed between DOACs and VKAs in cardiovascular mortality, all-cause mortality, ischemic/uncertain type of stroke or transient ischemic attack, or major or life-threatening bleeding in patients with AF on chronic hemodialysis.
Keyphrases
- direct oral anticoagulants
- atrial fibrillation
- systematic review
- cerebral ischemia
- venous thromboembolism
- peritoneal dialysis
- end stage renal disease
- chronic kidney disease
- ischemia reperfusion injury
- cardiovascular events
- subarachnoid hemorrhage
- meta analyses
- risk factors
- randomized controlled trial
- blood brain barrier
- type diabetes
- brain injury
- coronary artery disease