Ursodeoxycholic acid in the management of symptomatic gallstone disease: systematic review and clinician survey.
Lewis HallJames Halle-SmithRichard EvansGiles ToogoodTom WigginsSheraz R MarkarSpyros KapoulasPaul SuperOlga TuckerSiobhan C McKayPublished in: BJS open (2023)
Evidence for UDCA in symptomatic gallstones is scarce and heterogenous. Clinicians currently managing symptomatic gallstone disease are largely unaware of the benefit of UDCA, and there is clinical equipoise surrounding the benefit of UDCA. Level 1 evidence is required by clinicians to support UDCA use in the future.