Microbial biofilms and the human skin microbiome.
Michael BrandweinDoron SteinbergShiri MeshnerPublished in: NPJ biofilms and microbiomes (2016)
The human skin microbiome plays an important role in both health and disease. Microbial biofilms are a well-characterized mode of surface-associated growth, which present community-like behaviors. Additionally, biofilms are a critical element in certain skin diseases. We review how the perception of the resident skin microbiota has evolved from the early linkages of certain microbes to disease states, to a more comprehensive and intricate understanding brought on by biofilm and microbiome revelations. Rapidly expanding arsenals of experimental methods are opening new horizons in the study of human-microbe and microbe-microbe interactions. Microbial community profiling has largely remained a separate discipline from that of biofilm research, yet the introduction of metatranscriptomics, metabolomics, and the ability to distinguish between dormant and active members of a community have all paved the road toward a convergent cognizance of the encounter between these two microbial disciplines.
Keyphrases
- microbial community
- candida albicans
- mental health
- healthcare
- antibiotic resistance genes
- pseudomonas aeruginosa
- biofilm formation
- staphylococcus aureus
- endothelial cells
- soft tissue
- wound healing
- mass spectrometry
- patient safety
- single cell
- risk assessment
- induced pluripotent stem cells
- quality improvement
- health information
- health promotion
- pluripotent stem cells
- social media